FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling

Genome editing and human induced pluripotent stem cells hold great promise for the development of isogenic disease models and the correction of disease-associated mutations for isogenic tissue therapy. CRISPR-Cas9 has emerged as a versatile and simple tool for engineering human cells for such purpos...

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Publicat a:Stem Cell Reports
Autors principals: Arias-Fuenzalida, Jonathan, Jarazo, Javier, Qing, Xiaobing, Walter, Jonas, Gomez-Giro, Gemma, Nickels, Sarah Louise, Zaehres, Holm, Schöler, Hans Robert, Schwamborn, Jens Christian
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830965/
https://ncbi.nlm.nih.gov/pubmed/28988985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.08.026
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