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Argonaute 2 Is Required for Extra-embryonic Endoderm Differentiation of Mouse Embryonic Stem Cells

In mouse, although four Argonaute (AGO) proteins with partly overlapping functions in small-RNA pathways exist, only Ago2 deficiency causes embryonic lethality. To investigate the role of AGO2 during mouse early development, we generated Ago2-deficient mouse embryonic stem cells (mESCs) and performe...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Ngondo, Richard Patryk, Cirera-Salinas, Daniel, Yu, Jian, Wischnewski, Harry, Bodak, Maxime, Vandormael-Pournin, Sandrine, Geiselmann, Anna, Wettstein, Rahel, Luitz, Janina, Cohen-Tannoudji, Michel, Ciaudo, Constance
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830960/
https://ncbi.nlm.nih.gov/pubmed/29396181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.12.023
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