Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner

Human vision relies heavily upon cone photoreceptors, and their loss results in permanent visual impairment. Transplantation of healthy photoreceptors can restore visual function in models of inherited blindness, a process previously understood to arise by donor cell integration within the host reti...

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Publicado en:Stem Cell Reports
Main Authors: Waldron, Paul V., Di Marco, Fabiana, Kruczek, Kamil, Ribeiro, Joana, Graca, Anna B., Hippert, Claire, Aghaizu, Nozie D., Kalargyrou, Aikaterini A., Barber, Amanda C., Grimaldi, Giulia, Duran, Yanai, Blackford, Samuel J.I., Kloc, Magdalena, Goh, Debbie, Zabala Aldunate, Eduardo, Sampson, Robert D., Bainbridge, James W.B., Smith, Alexander J., Gonzalez-Cordero, Anai, Sowden, Jane C., Ali, Robin R., Pearson, Rachael A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830910/
https://ncbi.nlm.nih.gov/pubmed/29307580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.12.008
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