Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors

Photoreceptor replacement by transplantation is proposed as a treatment for blindness. Transplantation of healthy photoreceptor precursor cells into diseased murine eyes leads to the presence of functional photoreceptors within host retinae that express an array of donor-specific proteins. The resul...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Pearson, R. A., Gonzalez-Cordero, A., West, E. L., Ribeiro, J. R., Aghaizu, N., Goh, D., Sampson, R. D., Georgiadis, A., Waldron, P. V., Duran, Y., Naeem, A., Kloc, M., Cristante, E., Kruczek, K., Warre-Cornish, K., Sowden, J. C., Smith, A. J., Ali, R. R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059468/
https://ncbi.nlm.nih.gov/pubmed/27701378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13029
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