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Molecular Dynamics Simulations Reveal an Interplay between SHAPE Reagent Binding and RNA Flexibility
[Image: see text] The function of RNA molecules usually depends on their overall fold and on the presence of specific structural motifs. Chemical probing methods are routinely used in combination with nearest-neighbor models to determine RNA secondary structure. Among the available methods, SHAPE is...
Uloženo v:
| Vydáno v: | J Phys Chem Lett |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical
Society
2017
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5830694/ https://ncbi.nlm.nih.gov/pubmed/29265824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.7b02921 |
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