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MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation

Nuclear receptor coactivator 3 (NCOA3) is a transcriptional coactivator that has elevated expression in multiple tumor types, including colorectal cancer (CRC). However, the molecular mechanisms that regulate the tumorigenic functions of NCOA3 in CRC remain largely unknown. In this study, we aimed t...

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Bibliografiske detaljer
Udgivet i:Mol Oncol
Main Authors: Li, Yixin, Li, Liren, Chen, Miao, Yu, Xinfa, Gu, Zhuoyu, Qiu, Huijuan, Qin, Ge, Long, Qian, Fu, Xiaoyan, Liu, Tianze, Li, Wenbin, Huang, Wenlin, Shi, Dingbo, Kang, Tiebang, Luo, Meihua, Wu, Xiaojun, Deng, Wuguo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830628/
https://ncbi.nlm.nih.gov/pubmed/29360267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12173
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