Combined activity of COX-1 and COX-2 is increased in non-neoplastic colonic mucosa from colorectal neoplasia patients

BACKGROUND: Cyclooxygenase (COX) activity is increased in endoscopic normal colonic mucosa from patients with colorectal neoplasia (CRN). COX-2 is thought to be the predominant COX isozyme involved in neoplasia. Meanwhile, relative contributions of COX-1 and COX-2 isoforms are unknown. Knowledge abo...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Jensen, Thorbjørn Søren Rønn, Mahmood, Badar, Damm, Morten Bach, Backe, Marie Balslev, Dahllöf, Mattias Salling, Poulsen, Steen Seier, Hansen, Mark Berner, Bindslev, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830335/
https://ncbi.nlm.nih.gov/pubmed/29486731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-018-0759-1
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