Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

BACKGROUND: Intracellular signaling through cyclic nucleotides, both cyclic AMP and cyclic GMP, is altered in colorectal cancer. Accordingly, it is hypothesized that an underlying mechanism for colorectal neoplasia involves altered function of phosphodiesterases (PDEs), which affects cyclic nucleoti...

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Dettagli Bibliografici
Pubblicato in:BMC Cancer
Autori principali: Mahmood, Badar, Damm, Morten Matthiesen Bach, Jensen, Thorbjørn Søren Rønn, Backe, Marie Balslev, Dahllöf, Mattias Salling, Poulsen, Steen Seier, Bindslev, Niels, Hansen, Mark Berner
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141637/
https://ncbi.nlm.nih.gov/pubmed/27927168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2980-z
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