Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

BACKGROUND: Intracellular signaling through cyclic nucleotides, both cyclic AMP and cyclic GMP, is altered in colorectal cancer. Accordingly, it is hypothesized that an underlying mechanism for colorectal neoplasia involves altered function of phosphodiesterases (PDEs), which affects cyclic nucleoti...

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Udgivet i:BMC Cancer
Main Authors: Mahmood, Badar, Damm, Morten Matthiesen Bach, Jensen, Thorbjørn Søren Rønn, Backe, Marie Balslev, Dahllöf, Mattias Salling, Poulsen, Steen Seier, Bindslev, Niels, Hansen, Mark Berner
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141637/
https://ncbi.nlm.nih.gov/pubmed/27927168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2980-z
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