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Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

BACKGROUND: Intracellular signaling through cyclic nucleotides, both cyclic AMP and cyclic GMP, is altered in colorectal cancer. Accordingly, it is hypothesized that an underlying mechanism for colorectal neoplasia involves altered function of phosphodiesterases (PDEs), which affects cyclic nucleoti...

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Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Mahmood, Badar, Damm, Morten Matthiesen Bach, Jensen, Thorbjørn Søren Rønn, Backe, Marie Balslev, Dahllöf, Mattias Salling, Poulsen, Steen Seier, Bindslev, Niels, Hansen, Mark Berner
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141637/
https://ncbi.nlm.nih.gov/pubmed/27927168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2980-z
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