AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1

Adenosine monophosphate (AMP)–activated protein kinase (AMPK) acts as a master regulator of cellular energy homeostasis by directly phosphorylating metabolic enzymes and nutrient transporters and by indirectly promoting the transactivation of nuclear genes involved in mitochondrial biogenesis and fu...

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Publicat a:Sci Signal
Autors principals: Marin, Traci L., Gongol, Brendan, Zhang, Fan, Martin, Marcy, Johnson, David A., Xiao, Han, Wang, Yinsheng, Subramaniam, Shankar, Chien, Shu, Shyy, John Y.-J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830108/
https://ncbi.nlm.nih.gov/pubmed/28143904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf7478
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