AMPK and SIRT1 Coregulation of Cortactin Contributes to Endothelial Function

OBJECTIVE: Cortactin translocates to the cell periphery in vascular endothelial cells (ECs) upon cortical actin assembly in response to pulsatile shear stress. Because cortactin has putative sites for AMP-activated protein kinase (AMPK) phosphorylation and sirtuin 1 (SIRT1) deacetylation, we examine...

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Publicado en:Arterioscler Thromb Vasc Biol
Main Authors: Shentu, Tzu-Pin, He, Ming, Sun, Xiaoli, Zhang, Jianlin, Zhang, Fan, Gongol, Brendan, Marin, Traci L., Zhang, Jiao, Wen, Liang, Wang, Yinsheng, Geary, Gregory G., Zhu, Yi, Johnson, David A., Shyy, John Y.-J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391843/
https://ncbi.nlm.nih.gov/pubmed/27758765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307871
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