TLR4-mediated autophagic impairment contributes to neuropathic pain in chronic constriction injury mice

Neuropathic pain is a complex, chronic pain state characterized by hyperalgesia, allodynia, and spontaneous pain. Accumulating evidence has indicated that the microglial Toll-like receptor 4 (TLR4) and autophagy are implicated in neurodegenerative diseases, but their relationship and role in neuropa...

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Publicado en:Mol Brain
Autores principales: Piao, Yibo, Gwon, Do Hyeong, Kang, Dong-Wook, Hwang, Tae Woong, Shin, Nara, Kwon, Hyeok Hee, Shin, Hyo Jung, Yin, Yuhua, Kim, Jwa-Jin, Hong, Jinpyo, Kim, Hyun-Woo, Kim, Yonghyun, Kim, Sang Ryong, Oh, Sang-Ha, Kim, Dong Woon
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830083/
https://ncbi.nlm.nih.gov/pubmed/29486776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-018-0354-y
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