Regulation of androgen receptor activity by transient interactions of its transactivation domain with general transcription regulators

The androgen receptor is a transcription factor that plays a key role in the development of prostate cancer and its interactions with general transcription regulators are therefore of potential therapeutic interest. The mechanistic basis of these interactions is poorly understood due to the intrinsi...

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Vydáno v:Structure
Hlavní autoři: De Mol, Eva, Szulc, Elzbieta, Di Sanza, Claudio, Martínez-Cristóbal, Paula, Bertoncini, Carlos W., Fenwick, R. Bryn, Frigolé-Vivas, Marta, Masín, Marianela, Hunter, Irene, Buzón, Víctor, Brun-Heath, Isabelle, García, Jesús, De Fabritiis, Gianni, Estébanez-Perpiñá, Eva, McEwan, Iain J., Nebreda, Ángel R., Salvatella, Xavier
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830076/
https://ncbi.nlm.nih.gov/pubmed/29225078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.11.007
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