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TADs are 3D structural units of higher-order chromosome organization in Drosophila

Deciphering the rules of genome folding in the cell nucleus is essential to understand its functions. Recent chromosome conformation capture (Hi-C) studies have revealed that the genome is partitioned into topologically associating domains (TADs), which demarcate functional epigenetic domains define...

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Publicat a:Sci Adv
Autors principals: Szabo, Quentin, Jost, Daniel, Chang, Jia-Ming, Cattoni, Diego I., Papadopoulos, Giorgio L., Bonev, Boyan, Sexton, Tom, Gurgo, Julian, Jacquier, Caroline, Nollmann, Marcelo, Bantignies, Frédéric, Cavalli, Giacomo
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829972/
https://ncbi.nlm.nih.gov/pubmed/29503869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aar8082
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