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Repurposing the anthelmintic drug niclosamide to combat Helicobacter pylori

There is an urgent need to discover novel antimicrobial therapies. Drug repurposing can reduce the time and cost risk associated with drug development. We report the inhibitory effects of anthelmintic drugs (niclosamide, oxyclozanide, closantel, rafoxanide) against Helicobacter pylori strain 60190 a...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Tharmalingam, Nagendran, Port, Jenna, Castillo, Dawilmer, Mylonakis, Eleftherios
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829259/
https://ncbi.nlm.nih.gov/pubmed/29487357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22037-x
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