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Repurposing the anthelmintic drug niclosamide to combat Helicobacter pylori

There is an urgent need to discover novel antimicrobial therapies. Drug repurposing can reduce the time and cost risk associated with drug development. We report the inhibitory effects of anthelmintic drugs (niclosamide, oxyclozanide, closantel, rafoxanide) against Helicobacter pylori strain 60190 a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tharmalingam, Nagendran, Port, Jenna, Castillo, Dawilmer, Mylonakis, Eleftherios
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829259/
https://ncbi.nlm.nih.gov/pubmed/29487357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22037-x
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