Evaluation of Polygenic Determinants of Non-Alcoholic Fatty Liver Disease (NAFLD) By a Candidate Genes Resequencing Strategy

NAFLD is a polygenic condition but the individual and cumulative contribution of identified genes remains to be established. To get additional insight into the genetic architecture of NAFLD, GWAS-identified GCKR, PPP1R3B, NCAN, LYPLAL1 and TM6SF2 genes were resequenced by next generation sequencing...

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Udgivet i:Sci Rep
Main Authors: Di Costanzo, Alessia, Belardinilli, Francesca, Bailetti, Diego, Sponziello, Marialuisa, D’Erasmo, Laura, Polimeni, Licia, Baratta, Francesco, Pastori, Daniele, Ceci, Fabrizio, Montali, Anna, Girelli, Gabriella, De Masi, Bruna, Angeloni, Antonio, Giannini, Giuseppe, Del Ben, Maria, Angelico, Francesco, Arca, Marcello
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829219/
https://ncbi.nlm.nih.gov/pubmed/29487372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21939-0
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