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Synthesis of an Al(18)F radiofluorinated GLU-UREA-LYS(AHX)-HBED-CC PSMA ligand in an automated synthesis platform

BACKGROUND: Overexpression of prostatic membrane antigen (PSMA) is associated with the progression and prognosis of prostate cancer. There are numerous studies using this peptide with the (68)Ga radionuclide. Previous methods to synthetize (18)F–labeled PSMA ligands with complexes [(18)F]AlF(2+) hav...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EJNMMI Radiopharm Chem
Prif Awduron: Giglio, Javier, Zeni, Maia, Savio, Eduardo, Engler, Henry
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829129/
https://ncbi.nlm.nih.gov/pubmed/29503861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-018-0039-y
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