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Synthesis of an Al(18)F radiofluorinated GLU-UREA-LYS(AHX)-HBED-CC PSMA ligand in an automated synthesis platform

BACKGROUND: Overexpression of prostatic membrane antigen (PSMA) is associated with the progression and prognosis of prostate cancer. There are numerous studies using this peptide with the (68)Ga radionuclide. Previous methods to synthetize (18)F–labeled PSMA ligands with complexes [(18)F]AlF(2+) hav...

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Publicat a:EJNMMI Radiopharm Chem
Autors principals: Giglio, Javier, Zeni, Maia, Savio, Eduardo, Engler, Henry
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829129/
https://ncbi.nlm.nih.gov/pubmed/29503861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-018-0039-y
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