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Synthesis and preclinical evaluation of an Al(18)F radiofluorinated GLU-UREA-LYS(AHX)-HBED-CC PSMA ligand

PURPOSE: The aim of this study was to synthesize and preclinically evaluate an (18)F-PSMA positron emission tomography (PET) tracer. Prostate-specific membrane antigen (PSMA) specificity, biodistribution, and dosimetry in healthy and tumor-bearing mice were determined. METHODS: Several conditions fo...

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Detalhes bibliográficos
Publicado no:Eur J Nucl Med Mol Imaging
Main Authors: Boschi, Stefano, Lee, Jason T., Beykan, Seval, Slavik, Roger, Wei, Liu, Spick, Claudio, Eberlein, Uta, Buck, Andreas K., Lodi, Filippo, Cicoria, Gianfranco, Czernin, Johannes, Lassmann, Michael, Fanti, Stefano, Herrmann, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050145/
https://ncbi.nlm.nih.gov/pubmed/27329046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-016-3437-y
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