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Using human ‘experiments of nature’ to predict drug safety issues: an example with PCSK9 inhibitors

INTRODUCTION: When a new drug enters the market, its full array of side effects remains to be defined. Current surveillance approaches targeting these effects remain largely reactive. There is a need for development of methods to predict specific safety events that should be sought for a given new d...

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Detalhes bibliográficos
Publicado no:Drug Saf
Main Authors: Jerome, Rebecca N., Pulley, Jill M., Roden, Dan M., Shirey-Rice, Jana K., Bastarache, Lisa A., Bernard, Gordon, Ekstrom, Leeland, Lancaster, William J., Denny, Joshua C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828879/
https://ncbi.nlm.nih.gov/pubmed/29185237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-017-0616-0
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