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Circadian clock-dependent and -independent posttranscriptional regulation underlies temporal mRNA accumulation in mouse liver

The mammalian circadian clock coordinates physiology with environmental cycles through the regulation of daily oscillations of gene expression. Thousands of transcripts exhibit rhythmic accumulations across mouse tissues, as determined by the balance of their synthesis and degradation. While diurnal...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Jingkui, Symul, Laura, Yeung, Jake, Gobet, Cédric, Sobel, Jonathan, Lück, Sarah, Westermark, Pål O., Molina, Nacho, Naef, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828596/
https://ncbi.nlm.nih.gov/pubmed/29432155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715225115
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