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Lipid bilayer composition modulates the unfolding free energy of a knotted α-helical membrane protein
α-Helical membrane proteins have eluded investigation of their thermodynamic stability in lipid bilayers. Reversible denaturation curves have enabled some headway in determining unfolding free energies. However, these parameters have been limited to detergent micelles or lipid bicelles, which do not...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828594/ https://ncbi.nlm.nih.gov/pubmed/29432185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714668115 |
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