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Lipid bilayer composition modulates the unfolding free energy of a knotted α-helical membrane protein
α-Helical membrane proteins have eluded investigation of their thermodynamic stability in lipid bilayers. Reversible denaturation curves have enabled some headway in determining unfolding free energies. However, these parameters have been limited to detergent micelles or lipid bicelles, which do not...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828594/ https://ncbi.nlm.nih.gov/pubmed/29432185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714668115 |
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