Passive Transfer of Immune Sera Induced by a Zika Virus-Like Particle Vaccine Protects AG129 Mice Against Lethal Zika Virus Challenge

Zika virus (ZIKV) poses a serious public health threat due to its association with birth defects in developing fetuses and Guillain-Barré Syndrome in adults. We are developing a ZIKV vaccine based on virus-like particles (VLPs) generated in transiently transfected HEK293 cells. The genetic construct...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Autores principales: Espinosa, Diego, Mendy, Jason, Manayani, Darly, Vang, Lo, Wang, Chunling, Richard, Tiffany, Guenther, Ben, Aruri, Jayavani, Avanzini, Jenny, Garduno, Fermin, Farness, Peggy, Gurwith, Marc, Smith, Jon, Harris, Eva, Alexander, Jeff
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828544/
https://ncbi.nlm.nih.gov/pubmed/29269041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.12.010
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