Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis

BACKGROUND: Systemic autoimmunity can be present years before clinical onset of rheumatoid arthritis (RA). Adaptive immunity is initiated in lymphoid tissue where lymph node stromal cells (LNSCs) regulate immune responses through their intimate connection with leucocytes. We postulate that malfuncti...

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Publicado en:Arthritis Res Ther
Autores principales: Hähnlein, Janine S., Nadafi, Reza, de Jong, Tineke, Ramwadhdoebe, Tamara H., Semmelink, Johanna F., Maijer, Karen I., Zijlstra, IJsbrand A., Maas, Mario, Gerlag, Danielle M., Geijtenbeek, Teunis B. H., Tak, Paul P., Mebius, Reina E., van Baarsen, Lisa G. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828373/
https://ncbi.nlm.nih.gov/pubmed/29482663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1529-8
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