Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis

BACKGROUND: Systemic autoimmunity can be present years before clinical onset of rheumatoid arthritis (RA). Adaptive immunity is initiated in lymphoid tissue where lymph node stromal cells (LNSCs) regulate immune responses through their intimate connection with leucocytes. We postulate that malfuncti...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Hähnlein, Janine S., Nadafi, Reza, de Jong, Tineke, Ramwadhdoebe, Tamara H., Semmelink, Johanna F., Maijer, Karen I., Zijlstra, IJsbrand A., Maas, Mario, Gerlag, Danielle M., Geijtenbeek, Teunis B. H., Tak, Paul P., Mebius, Reina E., van Baarsen, Lisa G. M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828373/
https://ncbi.nlm.nih.gov/pubmed/29482663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1529-8
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