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Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis

Background: In rheumatoid arthritis (RA) the cause for loss of tolerance and anti-citrullinated protein antibody (ACPA) production remains unidentified. Mouse studies showed that lymph node stromal cells (LNSCs) maintain peripheral tolerance through presentation of peripheral tissue antigens (PTAs)....

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Hähnlein, Janine S., Nadafi, Reza, de Jong, Tineke A., Semmelink, Johanna F., Remmerswaal, Ester B. M., Safy, Mary, van Lienden, Krijn P., Maas, Mario, Gerlag, Danielle M., Tak, Paul P., Mebius, Reina E., Wähämaa, Heidi, Catrina, Anca I., G. M. van Baarsen, Lisa
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460812/
https://ncbi.nlm.nih.gov/pubmed/32784936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165713
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