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Independent functions of DNMT1 and USP7 at replication foci

BACKGROUND: It has been reported that USP7 (ubiquitin-specific protease 7) prevents ubiquitylation and degradation of DNA methyltransferase 1 (DNMT1) by direct binding of USP7 to the glycine-lysine (GK) repeats that join the N-terminal regulatory domain of DNMT1 to the C-terminal methyltransferase d...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Yarychkivska, Olya, Tavana, Omid, Gu, Wei, Bestor, Timothy H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828336/
https://ncbi.nlm.nih.gov/pubmed/29482658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0179-z
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