ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model

BACKGROUND: The LIM-homeobox transcription factor islet-1 (ISL1) has been proposed as a marker for cardiovascular progenitor cells. This study investigated whether forced expression of ISL1 in human mesenchymal stem cells (hMSCs) improves myocardial infarction (MI) treatment outcomes. METHODS: The l...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Xiang, Qiuling, Liao, Yan, Chao, Hua, Huang, Weijun, Liu, Jia, Chen, Haixuan, Hong, Dongxi, Zou, Zhengwei, Xiang, Andy Peng, Li, Weiqiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828309/
https://ncbi.nlm.nih.gov/pubmed/29482621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0803-7
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