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Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis

Angiogenesis, a prominent feature of pathology, is known to be guided by factors secreted by living cells around a lesion. Although many cells are disrupted in a response to injury, the relevance of degenerating cells in pathological angiogenesis is unclear. Here, we show that the release of lactate...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Lin, Hsiaoyun, Muramatsu, Rieko, Maedera, Noriko, Tsunematsu, Hiroto, Hamaguchi, Machika, Koyama, Yoshihisa, Kuroda, Mariko, Ono, Kenji, Sawada, Makoto, Yamashita, Toshihide
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828296/
https://ncbi.nlm.nih.gov/pubmed/29248508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.10.033
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