Peripherally derived FGF21 promotes remyelination in the central nervous system

Demyelination in the central nervous system (CNS) leads to severe neurological deficits that can be partially reversed by spontaneous remyelination. Because the CNS is isolated from the peripheral milieu by the blood-brain barrier, remyelination is thought to be controlled by the CNS microenvironmen...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kuroda, Mariko, Muramatsu, Rieko, Maedera, Noriko, Koyama, Yoshihisa, Hamaguchi, Machika, Fujimura, Harutoshi, Yoshida, Mari, Konishi, Morichika, Itoh, Nobuyuki, Mochizuki, Hideki, Yamashita, Toshihide
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669554/
https://ncbi.nlm.nih.gov/pubmed/28825598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94337
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