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Assessment of pazopanib-related hypertension, cardiac dysfunction and identification of clinical risk factors for their development

BACKGROUND: Antineoplastic therapy with the tyrosine kinase inhibitor pazopanib in patients with advanced/metastatic renal cell carcinoma (mRCC) has been associated with hypertension (HTN), cardiomyopathy, and cardiac dysrhythmias. We therefore assessed the cardiovascular (CV) risk with pazopanib in...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cardiooncology
Auteurs principaux: Pinkhas, Daniel, Ho, Thai, Smith, Sakima
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828231/
https://ncbi.nlm.nih.gov/pubmed/29497565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40959-017-0024-8
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