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Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors

A suitable clinical-grade platform is required for detection of somatic mutations with high sensitivity in cell-free DNA (cfDNA) of patients with solid tumors. In this study, we evaluated in parallel ultra-deep NGS with MassARRAY and allele-specific droplet digital PCR (ddPCR) for cfDNA genotyping a...

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Pubblicato in:Oncotarget
Autori principali: Mehrotra, Meenakshi, Singh, Rajesh R., Loghavi, Sanam, Duose, Dzifa Yawa, Barkoh, Bedia A., Behrens, Carmen, Patel, Keyur P., Routbort, Mark J., Kopetz, Scott, Broaddus, Russell R., Medeiros, L. Jeffrey, Wistuba, Ignacio I., Luthra, Rajyalakshmi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828199/
https://ncbi.nlm.nih.gov/pubmed/29535804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21982
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