Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors

A suitable clinical-grade platform is required for detection of somatic mutations with high sensitivity in cell-free DNA (cfDNA) of patients with solid tumors. In this study, we evaluated in parallel ultra-deep NGS with MassARRAY and allele-specific droplet digital PCR (ddPCR) for cfDNA genotyping a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mehrotra, Meenakshi, Singh, Rajesh R., Loghavi, Sanam, Duose, Dzifa Yawa, Barkoh, Bedia A., Behrens, Carmen, Patel, Keyur P., Routbort, Mark J., Kopetz, Scott, Broaddus, Russell R., Medeiros, L. Jeffrey, Wistuba, Ignacio I., Luthra, Rajyalakshmi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828199/
https://ncbi.nlm.nih.gov/pubmed/29535804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21982
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