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Multidimensional control of Cas9 by evolved RNA polymerase-based biosensors
Systems to control Cas9 with spatial and temporal precision offer opportunities to decrease side effects, protect sensitive tissues, and create gene therapies that are only activated at defined times and places. Here, we present the design of new Cas9 controllers based on RNA polymerase (RNAP)-based...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828011/ https://ncbi.nlm.nih.gov/pubmed/28809467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00532 |
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