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Dissecting gene-environment interactions: a penalized robust approach accounting for hierarchical structures

Identification of gene–environment (G×E) interactions associated with disease phenotypes has posed a great challenge in high-throughput cancer studies. The existing marginal identification methods have suffered from not being able to accommodate the joint effects of a large number of genetic variant...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Wu, Cen, Jiang, Yu, Ren, Jie, Cui, Yuehua, Ma, Shuangge
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827955/
https://ncbi.nlm.nih.gov/pubmed/29034484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7518
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