Light-triggered RNA release and induction of hMSC osteogenesis via photodegradable, dual-crosslinked hydrogels

AIM: To engineer a photodegradable hydrogel system for actively controlled release of bioactive unmodified RNA at designated time points to induce hMSC osteogenesis. MATERIALS & METHODS: RNA/polyethylenimine complexes were loaded into dual-crosslinked photodegradable hydrogels to examine the cap...

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Detalhes bibliográficos
Publicado no:Nanomedicine (Lond)
Main Authors: Huynh, Cong Truc, Nguyen, Minh Khanh, Naris, Mantas, Tonga, Gulen Yesilbag, Rotello, Vincent M, Alsberg, Eben
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827787/
https://ncbi.nlm.nih.gov/pubmed/27246686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2016-0088
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