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A comparison of hMSC osteogenesis in PEG hydrogels as a function of MMP-sensitive crosslinker and crosslink density in chemically-defined medium

This study investigated osteogenesis of human mesenchymal stem cells (hMSCs) encapsulated in matrix-metalloproteinase (MMP)-sensitive poly(ethylene glycol) (PEG) hydrogels in chemically-defined medium (10 ng/ml BMP-2). Thiol-norbornene photoclick hydrogels were formed with CRGDS and crosslinkers of...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Aziz, Aaron H., Bryant, Stephanie J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938297/
https://ncbi.nlm.nih.gov/pubmed/30776309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26957
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