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Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model

Opioid analgesics are frequently prescribed in the United States and worldwide. However, serious comorbidities, such as dependence, tolerance, immunosuppression and gastrointestinal disorders limit their long-term use. In the current study, a morphine-murine model was used to investigate the role of...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wang, Fuyuan, Meng, Jingjing, Zhang, Li, Johnson, Timothy, Chen, Chi, Roy, Sabita
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827657/
https://ncbi.nlm.nih.gov/pubmed/29483538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21915-8
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