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The oncolytic virus ΔPK has multimodal anti-tumor activity

Oncolytic viruses (OVs) are an emerging cancer therapeutic, with a near complete absence of serious adverse effects. However, clinical efficacy is relatively modest, related to poor tumor penetration, failure to lyse cancer stem cells (CSCs) and blockade of immunogenic cell death by the immunosuppre...

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Detalhes bibliográficos
Publicado no:Pathog Dis
Main Authors: Aurelian, Laure, Bollino, Dominique, Colunga, Aric
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827585/
https://ncbi.nlm.nih.gov/pubmed/27242376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftw050
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