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Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein
The heterodimeric human (h) electron-transferring flavoprotein (ETF) transfers electrons from at least 13 different flavin dehydrogenases to the mitochondrial respiratory chain through a non-covalently bound FAD cofactor. Here, we describe the discovery of an irreversible and pH-dependent oxidation...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5827430/ https://ncbi.nlm.nih.gov/pubmed/29301933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000846 |
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