The Host Factor AUF1 p45 Supports Flavivirus Propagation by Triggering the RNA Switch Required for Viral Genome Cyclization

In previous studies, we showed that the cellular RNA-binding protein AUF1 supports the replication process of the flavivirus West Nile virus. Here we demonstrate that the protein also enables effective proliferation of dengue virus and Zika virus, indicating that AUF1 is a general flavivirus host fa...

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發表在:J Virol
Main Authors: Friedrich, Susann, Engelmann, Susanne, Schmidt, Tobias, Szczepankiewicz, Grit, Bergs, Sandra, Liebert, Uwe G., Kümmerer, Beate M., Golbik, Ralph P., Behrens, Sven-Erik
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
主題:
Genome Replication and Regulation of Viral Gene Expression
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827407/
https://ncbi.nlm.nih.gov/pubmed/29263261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01647-17
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