The Host Factor AUF1 p45 Supports Flavivirus Propagation by Triggering the RNA Switch Required for Viral Genome Cyclization

In previous studies, we showed that the cellular RNA-binding protein AUF1 supports the replication process of the flavivirus West Nile virus. Here we demonstrate that the protein also enables effective proliferation of dengue virus and Zika virus, indicating that AUF1 is a general flavivirus host fa...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Friedrich, Susann, Engelmann, Susanne, Schmidt, Tobias, Szczepankiewicz, Grit, Bergs, Sandra, Liebert, Uwe G., Kümmerer, Beate M., Golbik, Ralph P., Behrens, Sven-Erik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2018
Konular:
Genome Replication and Regulation of Viral Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827407/
https://ncbi.nlm.nih.gov/pubmed/29263261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01647-17
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