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Sim3C: simulation of Hi-C and Meta3C proximity ligation sequencing technologies

BACKGROUND: Chromosome conformation capture (3C) and Hi-C DNA sequencing methods have rapidly advanced our understanding of the spatial organization of genomes and metagenomes. Many variants of these protocols have been developed, each with their own strengths. Currently there is no systematic means...

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Библиографические подробности
Опубликовано в: :Gigascience
Главные авторы: DeMaere, Matthew Z, Darling, Aaron E
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827349/
https://ncbi.nlm.nih.gov/pubmed/29149264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/gix103
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