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Deconvoluting simulated metagenomes: the performance of hard- and soft- clustering algorithms applied to metagenomic chromosome conformation capture (3C)

BACKGROUND: Chromosome conformation capture, coupled with high throughput DNA sequencing in protocols like Hi-C and 3C-seq, has been proposed as a viable means of generating data to resolve the genomes of microorganisms living in naturally occuring environments. Metagenomic Hi-C and 3C-seq datasets...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: DeMaere, Matthew Z., Darling, Aaron E.
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103821/
https://ncbi.nlm.nih.gov/pubmed/27843713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2676
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