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Hypoxia, Hypoxia-Inducible Factor-1α, and Innate Antileishmanial Immune Responses

Low oxygen environments and accumulation of hypoxia-inducible factors (HIFs) are features of infected and inflamed tissues. Here, we summarize our current knowledge on oxygen levels found in Leishmania-infected tissues and discuss which mechanisms potentially contribute to local tissue oxygenation i...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Schatz, Valentin, Neubert, Patrick, Rieger, Franz, Jantsch, Jonathan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827161/
https://ncbi.nlm.nih.gov/pubmed/29520262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00216
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