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Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling

Targeted therapy has held promise to be a successful anticancer treatment due to its specificity towards tumor cells that express the target receptors. However, not all targeting drugs used in the clinic are equally effective in tumor eradication. To examine which biochemical and biophysical propert...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Karolak, Aleksandra, Estrella, Veronica C., Huynh, Amanda S., Chen, Tingan, Vagner, Josef, Morse, David L., Rejniak, Katarzyna A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827036/
https://ncbi.nlm.nih.gov/pubmed/29483578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21883-z
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