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The Role of Tumor Tissue Architecture in Treatment Penetration and Efficacy: An Integrative Study

Despite the great progress that has been made in understanding cancer biology and the potential molecular targets for its treatment, the majority of drugs fail in the clinical trials. This may be attributed (at least in part) to the complexity of interstitial drug transport in the patient’s body, wh...

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Detalhes bibliográficos
Main Authors: Rejniak, Katarzyna A., Estrella, Veronica, Chen, Tingan, Cohen, Allison S., Lloyd, Mark C., Morse, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650652/
https://ncbi.nlm.nih.gov/pubmed/23717812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00111
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