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Abrogation of TGF-beta signalling in TAGLN expressing cells recapitulates Pentalogy of Cantrell in the mouse

Pentalogy of Cantrell (PC) is a rare multi-organ congenital anomaly that impedes ventral body wall closure and results in diaphragmatic hernia, intra- and pericardial defects. The underlying cellular and molecular changes that lead to these severe developmental defects have remained unknown largely...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Aldeiri, Bashar, Roostalu, Urmas, Albertini, Alessandra, Behnsen, Julia, Wong, Jason, Morabito, Antonino, Cossu, Giulio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826924/
https://ncbi.nlm.nih.gov/pubmed/29483576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21948-z
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