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Transgelin-expressing myofibroblasts orchestrate ventral midline closure through TGFβ signalling

Ventral body wall (VBW) defects are among the most common congenital malformations, yet their embryonic origin and underlying molecular mechanisms remain poorly characterised. Transforming growth factor beta (TGFβ) signalling is essential for VBW closure, but the responding cells are not known. Here...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Aldeiri, Bashar, Roostalu, Urmas, Albertini, Alessandra, Wong, Jason, Morabito, Antonino, Cossu, Giulio
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612253/
https://ncbi.nlm.nih.gov/pubmed/28807903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.152843
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