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Transgelin-expressing myofibroblasts orchestrate ventral midline closure through TGFβ signalling

Ventral body wall (VBW) defects are among the most common congenital malformations, yet their embryonic origin and underlying molecular mechanisms remain poorly characterised. Transforming growth factor beta (TGFβ) signalling is essential for VBW closure, but the responding cells are not known. Here...

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Bibliografische gegevens
Gepubliceerd in:Development
Hoofdauteurs: Aldeiri, Bashar, Roostalu, Urmas, Albertini, Alessandra, Wong, Jason, Morabito, Antonino, Cossu, Giulio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612253/
https://ncbi.nlm.nih.gov/pubmed/28807903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.152843
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