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Long-range Telomere Regulation of Gene Expression: Telomere Looping and Telomere Position Effect Over Long Distances (TPE-OLD)

The human cellular reverse transcriptase, telomerase, is very tightly regulated in large long-lived species. Telomerase is expressed during early human fetal development, is turned off in most adult tissues, and then becomes reactivated in almost all human cancers. However, the exact mechanism regul...

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Detalhes bibliográficos
Publicado no:Differentiation
Main Authors: Kim, Wanil, Shay, Jerry W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826875/
https://ncbi.nlm.nih.gov/pubmed/29197683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2017.11.005
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